diuretic hydrochlorothiazide 2021-10-07T13:42:44Z CHEBI:5778 Dichlothiazide Dihydrochlorothiazide PMID:3611778 This is a thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. XCO:0000899 experimental_condition_ontology slaulede