part_of controlled in vitro cell condition PDGF-AA 2023-03-14T15:14:58Z PMID:26640375 This is any experimental condition in which the main influencing factor is a dimeric isoform of platelet-derived growth factor (PDGF-AA). All PDGF isoforms are potent mitogens for connective tissue cells, including dermal fibroblasts, glial cells, arterial smooth muscle cells and some epithelial and endothelial cells. PDGF appears to be ubiquitous in neurons throughout the CNS, where it is suggested to play an important role in neuron survival and regeneration, and in mediation of glial cell proliferation and differentiation. XCO:0000995 experimental_condition_ontology platelet-derived growth factor-AA platelet-derived growth factor-AA isoform platelet-derived growth factor-alpha/alpha isoform slaulede