ribonucleic acid scrambled control LNA-modified oligonucleotide 2023-06-27T13:16:05Z PMID:28760335 This is any condition in which the main influencing factor is a control locked nucleic acid (LNA)–modified oligonucleotide with a non-specific scrambled sequence. A locked nucleic acid (LNA), also known as bridged nucleic acid (BNA), and often referred to as inaccessible RNA, is a modified RNA nucleotide in which the ribose moiety is modified with an extra bridge connecting the 2' oxygen and 4' carbon. LNAs provide structural stability and nuclease resistance to the oligonucleotide. XCO:0001065 experimental_condition_ontology scrambled control BNA oligonucleotide scrambled control LNA oligonucleotide scrambled control locked nucleic acid oligonucleotide slaulede