vasodilator anti-inflammatory agent sinomenine 2024-03-01T11:26:11Z CHEBI:9163 MESH:C009271 PMID:61710 This is any condition in which the main influencing factor is sinomenine, a unique plant alkaloid that releases histamine in association with degranulation of tissue mast cells in mammalian tissues. Sinomenine has been used in herbal medicine for the treatment of rheumatism and arthritis. Sinomenine also has anti-angiogenic, anti-inflammatory, and anti-apoptotic effects. XCO:0001303 cocculine cucoline cuculine experimental_condition_ontology slaulederkind