has_component enzyme chemical nanoparticle anticoagulant urokinase-loaded nano-patrols 2025-05-05T16:09:21Z CHEBI:50803 PMID:34078604 This is any condition in which the main influencing factor is urokinase-loaded nano-patrols, which are mesoporous polydopamine nanoparticles which have been loaded with human urokinase and coated with three different single-stranded DNAs to function as thrombin aptamers, pore sealers, and release biomarkers. These specialized nanoparticles are used for regulating therapeutic urokinase dose based on the in vivo thrombolysis resistance of thrombi. XCO:0001614 experimental_condition_ontology slaulederkind uPA-loaded mesoporous polydopamine nanoparticles uPA-loaded nano-patrols uPA-loaded pDA nanoparticles urokinase-loaded mesoporous polydopamine nanoparticles