has_component nicotine multigenerational maternal exposure to nicotine 2025-10-27T17:01:35Z GEO:GSE291986 PMID:41013184 This is any condition in which the main influencing factor is any maternal exposure to nicotine that has multigenerational effects. This is a condition typically studied to determine the effect of maternal (F0) nicotine use/exposure on the F1 offspring, but can also affect the F2 generation by direct effects on the germline of the gestating or preweaning F1 offspring. The maternal exposure may be any time before pregnancy (pregestational) up to the time of weaning of offspring. XCO:0001750 experimental_condition_ontology multigenerational maternal exposure to (R,S)-nicotine multigenerational maternal exposure to nicotine tartrate slaulederkind