antimetabolite antineoplastic agent enzyme inhibitor hydroxyurea 2025-10-30T14:19:07Z CID:3657 GEO:GSE301071 N-hydroxyurea  PMID:37698739 This is any condition in which the main influencing factor is hydroxyurea, an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea  is used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. XCO:0001765 experimental_condition_ontology hydroxycarbamide slaulederkind