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    <!-- http://purl.obolibrary.org/obo/GO_0004175 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004175">
        <rdfs:label>endopeptidase activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008233"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/25813</ns3:IAO_0000233>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8932355</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8934819</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-68948</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-68825</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9912636</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-4641260</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-3640874</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9934884</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-6784676</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9912751</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-264458</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8850992</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9934887</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-187574</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-4641256</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>proteasome endopeptidase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1433374</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>GO:0016809</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9908780</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>proteinase</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-180573</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9008110</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-353125</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9906017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8952408</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9614271</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5610760</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174058</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5387392</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8939801</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9912655</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8852354</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9755303</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9755306</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5668520</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-180603</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1168640</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5658430</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-211715</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174202</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174203</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1236935</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5668481</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5607731</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8854071</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-188191</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9010096</oboInOwl:hasDbXref>
        <oboInOwl:id>GO:0004175</oboInOwl:id>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5635868</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-209061</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8866858</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9908108</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-69600</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8849797</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9604642</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174105</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1251997</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>elastase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2213200</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5635854</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-5610758</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9908101</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9762096</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-983158</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9009362</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>Reactome:R-HSA-69016</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-983150</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5687112</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-193682</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5358340</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5358460</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174255</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2130282</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9839376</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-450466</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-3928656</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1504193</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-4608855</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1236970</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5693081</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5362448</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-8866553</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>endoprotease activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9912747</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-75825</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9934893</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-8854044</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1234159</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-74730</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5607724</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-6784628</oboInOwl:hasDbXref>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0008233 -->

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        <rdfs:label>peptidase activity</rdfs:label>
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