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    <!-- http://purl.obolibrary.org/obo/GO_0004175 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004175">
        <rdfs:label>endopeptidase activity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0004197 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004197">
        <rdfs:label>cysteine-type endopeptidase activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0004175"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008234"/>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201630</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-201637</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201634</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-202967</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201595</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9694551</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-202960</oboInOwl:hasDbXref>
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        <oboInOwl:id>GO:0004197</oboInOwl:id>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-351901</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9647999</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201622</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5681987</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-352268</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9647632</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-139952</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201629</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9013895</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201628</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201611</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2130336</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9710101</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>metacaspase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9694732</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-6800797</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>thiol endopeptidase activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9684340</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9686088</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-202947</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>EC:3.4.22.-</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-418845</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-212552</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-264871</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-9603534</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-114259</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.</ns3:IAO_0000115>
        <oboInOwl:hasNarrowSynonym>caspase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-114252</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5634228</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9694338</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>Reactome:R-HSA-202917</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-351936</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9693929</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9684336</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-350158</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-114261</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9694377</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1678920</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2562564</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1236948</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>lysosomal cysteine-type endopeptidase</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-350319</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-350318</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9684309</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5660663</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9697750</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-351871</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201640</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2028697</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2028692</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-351876</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-351877</oboInOwl:hasDbXref>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0008234 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0008234">
        <rdfs:label>cysteine-type peptidase activity</rdfs:label>
    </Class>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



