<?xml version="1.0"?>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
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    <!-- http://purl.obolibrary.org/obo/GO_0004022 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004022">
        <rdfs:label>alcohol dehydrogenase (NAD+) activity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0004745 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004745">
        <rdfs:label>all-trans-retinol dehydrogenase (NAD+) activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0004022"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/20980</ns3:IAO_0000233>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/27136</ns3:IAO_0000233>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/28011</ns3:IAO_0000233>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5362518</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2454081</oboInOwl:hasDbXref>
        <oboInOwl:hasBroadSynonym>retinol dehydrogenase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2466832</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:RETINOL-DEHYDROGENASE-RXN</oboInOwl:hasDbXref>
        <oboInOwl:hasBroadSynonym>retinene reductase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>RHEA:48488</oboInOwl:hasDbXref>
        <oboInOwl:id>GO:0004745</oboInOwl:id>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
        <oboInOwl:hasBroadSynonym>all-trans retinol dehydrogenase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5362564</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Catalysis of the reaction: all-trans-retinol--[retinol-binding protein] + NAD+ = all-trans-retinal--[retinol-binding protein] + H+ + NADH. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein (CRBP1), but has higher affinity for the bound form.</ns3:IAO_0000115>
        <oboInOwl:hasBroadSynonym>retinol (vitamin A1) dehydrogenase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>retinal reductase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>EC:1.1.1.105</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5362721</oboInOwl:hasDbXref>
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