part_of part of part of in_anterior_side_of contributes to morphology of composed primarily of existence ends during immediate transformation of neural cell organ fully formed stage multicellular organism brain NCIT:C12439 The part of the central nervous system contained within the cranium, comprising the forebrain, midbrain, hindbrain, and metencephalon. It is derived from the anterior part of the embryonic neural tube (or the encephalon). Does not include retina. (CUMBO) requires review for applicability to invertebrate structures, e.g. synganglion DHBA:10155 GAID:571 EMAPA:16894 BTO:0000142 Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO] uberon MESH:D001921 EHDAA:6485 CALOHA:TS-0095 VHOG:0000157 EHDAA2:0000183 XAO:0000010 BAMS:Brain suprasegmental levels of nervous system Wikipedia:Brain FMA:50801 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=21 (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG] MBA:997 SCTID:258335003 EHDAA:2641 BAMS:Br synganglion galen:Brain TAO:0000008 MBA:8 Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system.[TAO] BILA:0000135 EV:0100164 EFO:0000302 HBA:4005 MAT:0000098 UMLS:C0006104 PBA:3999 ABA:Brain FBbt:00005095 ZFA:0000008 The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. MIAA:0000098 OpenCyc:Mx4rvVjT65wpEbGdrcN5Y29ycA AAO:0010478 UBERON:0000955 BIRNLEX:796 suprasegmental structures encephalon the brain UMLS:C1269537 MA:0000168 nervous system central nervous system ectoderm-derived structure future brain