submandibular gland http://upload.wikimedia.org/wikipedia/commons/5/51/Illu_quiz_hn_02.jpg MA:0001589 glandula submandibularis GAID:942 In mouse, multilobed and lobulated, on the ventral midline of the neck UMLS:C0038556 submandibular salivary gland BTO:0001316 The submandibular is the first major salivary gland to develop in the embryo, followed by the neighbouring sublingual and then the parotid.[PMID:17336109] lobular, sexually dimorphic in mouse Either of the paired compound tubuloalveolar (aka tubuloacinar) major salivary glands composed of both serous and mucous secretory cells and situated beneath the mandible. maxillary gland submaxillary gland CALOHA:TS-0988 VHOG:0000364 The term submandibular as used in humans, is incorrect due the difference in topography of these structures[http://www.avdc.org] In humans, they account for 70% of the salivary volume and weigh about 15 grams. [WP,unvetted] NCIT:C12233 MESH:D013363 mandibular salivary gland EFO:0001387 uberon Either of two major salivary glands situated in the neck near the lower edge of each side of the mandible and emptying into the submandibular duct. [TFD][VHOG] FMA:55093 The most common oral glands in mammals are the salivary glands. There are usually three primary pairs of salivary glands, named for their approximate positions: mandibular (submandibular or submaxillary), sublingual, and parotid.[well established][VHOG] EV:0100061 mandibular gland EMAPA:18812 in mice, submandibular gland development initiates as a thickening of the oral epithelium; around E12 an initial (single) epithelial bud on a stalk grows into a condensing neural crest-derived mesenchyme; clefts in the epithelium result in 3-5 epithelial buds at E13.5, and branching morphogenesis occurs with continued proliferation, successive rounds of cleft formation, duct elongation, and duct lumen formation, so that by E14 the gland is highly branched (multi-lobed); functional differentiation, with the appearance of proacinar cells and secretory products begins after E15 and continues to birth; acinar differentiation continues postnatally with final differentiation of the granular convoluted tubules at puberty[MGI:anna] UBERON:0001736 major salivary gland structure with developmental contribution from neural crest