develops_from develops from anatomical entity anatomical entity tissue lens placode lens vesicle lens mass EHDAA2:0000983 (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG] UBERON:0005426 presumptive lens the lens of zebrafish (and other teleosts) forms from delamination of cells from the lens placode; thus, there is no formation of a hollow lens vesicle, in contrast to the situation in mammals and birds (Glass and Dahm, 2004) [PMID:16496288] The lens of the zebrafish forms by delamination of lens placodal cells and not through invagination. This results in a solid spherical mass as opposed to a hollow lens vesicle. Detachment of the solid lens vesicle of zebrafish at 24b26 hpf is accomplished in part by apoptosis, similar to mammals SCTID:361510002 Portion of tissue that gives rise to the lens. VHOG:0001163 solid lens vesicle EMAPA:17163 immature lens TAO:0002205 ZFA:0001679 uberon A vesicle formed from the lens pit of the embryo, developing into the crystalline lens. [TFD][VHOG] EHDAA:4737 hollow lens vesicle