<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/CLO?iri=http://purl.obolibrary.org/obo/UBERON_0005876"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000008"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000003"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000001"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000012"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/depicted_by"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part_of</rdfs:label>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002160 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002160">
        <rdfs:label>only in taxon</rdfs:label>
        <rdfs:label>only_in_taxon</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002202 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002202">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>develops_from</rdfs:label>
        <rdfs:label xml:lang="en">develops from</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002387 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002387">
        <rdfs:label>has potential to develop into</rdfs:label>
        <rdfs:label xml:lang="en">has potential to develop into</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CARO_0000000 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CARO_0000000">
        <rdfs:label>anatomical entity</rdfs:label>
        <rdfs:label xml:lang="en">anatomical entity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_32524 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_32524">
        <rdfs:label>Amniota</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002050 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002050">
        <rdfs:label>embryonic structure</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004874 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004874">
        <rdfs:label>somatopleure</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0005876 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005876">
        <rdfs:label>undifferentiated genital tubercle</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0000000"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002050"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0009196"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002387"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0011757"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002160"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32524"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004874"/>
            </Restriction>
        </rdfs:subClassOf>
        <foaf:depicted_by rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png</foaf:depicted_by>
        <ns3:IAO_0000115>The embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin.</ns3:IAO_0000115>
        <ns3:UBPROP_0000008>todo - add taxon constraints</ns3:UBPROP_0000008>
        <oboInOwl:hasExactSynonym>undifferentiated genital tubercle</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>EHDAA:5925</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0000705</oboInOwl:hasDbXref>
        <ns3:UBPROP_0000008>GT development is indistinguishable in male and female mouse embryos until approximately E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP:0011771]</ns3:UBPROP_0000008>
        <ns3:UBPROP_0000003>In mammalian embryos, male and female external genitalia develop from the genital tubercle.[well established][VHOG]</ns3:UBPROP_0000003>
        <oboInOwl:hasRelatedSynonym>tuberculum phallicum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>tuberculum genitale</oboInOwl:hasRelatedSynonym>
        <ns3:UBPROP_0000001>The eminence in the embryo which develops into the clitoris or penis. [TFD][VHOG]</ns3:UBPROP_0000001>
        <oboInOwl:hasDbXref>VHOG:0000583</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>genital tubercle</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Genital_tubercle</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:302888</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:308798005</oboInOwl:hasDbXref>
        <ns3:UBPROP_0000001>embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin; GT development is indistinguishable in male and female mouse embryos until ~E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP]</ns3:UBPROP_0000001>
        <oboInOwl:hasRelatedSynonym>phallic tubercle</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <ns3:UBPROP_0000012>we assume the EMAPA class is the undifferentiated form based on TS timings</ns3:UBPROP_0000012>
        <oboInOwl:hasDbXref>EMAPA:17382</oboInOwl:hasDbXref>
        <oboInOwl:id>UBERON:0005876</oboInOwl:id>
        <ns3:UBPROP_0000008>All amniotes studied to date initiate external genital development with the formation of paired genital swellings. In mammals, archosaurs, and turtles, these swellings merge to form a single genital tubercle, the precursor of the penis and clitoris[PMID:24960313]</ns3:UBPROP_0000008>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0009196 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0009196">
        <rdfs:label>indifferent external genitalia</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0011757 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0011757">
        <rdfs:label>differentiated genital tubercle</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



