motor neuron disease spinal cord disease amyotrophic lateral sclerosis GeneRIF:11854285 MOTOR NEURON DIS AMYOTROPHIC LATERAL SCLEROSIS GeneRIF:11854284 GeneRIF:12584731 GeneRIF:12153483 GeneRIF:15350647 GeneRIF:12972170 GeneRIF:13678668 GeneRIF:12783432 GeneRIF:11991808 GeneRIF:12437574 GeneRIF:12270696 GeneRIF:12448348 GeneRIF:12393885 NIFSTD:birnlex_12566 Motor Neuron Disease, Amyotrophic Lateral Sclerosis GeneRIF:15837590 GeneRIF:14506936 GeneRIF:15546588 GeneRIF:12641746 GeneRIF:16114275 GeneRIF:15019581 GeneRIF:15623718 GeneRIF:12138710 GeneRIF:12866199 GeneRIF:11860274 Amyotrophic lateral sclerosis (disorder) GeneRIF:12614934 Amyotrophic Lateral Sclerosis, Guam Form GeneRIF:12875980 GeneRIF:16005901 GeneRIF:15488469 GeneRIF:11675877 GeneRIF:12528821 GeneRIF:12644909 GeneRIF:15006704 GeneRIF:15030390 GeneRIF:15094483 An autosomal dominant inherited form of amyloidosis. GeneRIF:14989597 GeneRIF:15388334 GeneRIF:12677446 GeneRIF:14511332 GeneRIF:12847526 GeneRIF:12458194 GeneRIF:14970233 GeneRIF:12210393 Disease, Lou-Gehrigs SNOMEDCT:86044005 GeneRIF:15910777 GeneRIF:14597108 GeneRIF:12679596 GeneRIF:15652414 Dementia With Amyotrophic Lateral Sclerosis GeneRIF:15313203 Lateral Scleroses, Amyotrophic GeneRIF:12870272 GeneRIF:12217886 Tomasz Adamusiak GeneRIF:14675609 GeneRIF:14642651 GeneRIF:15657392 AMYOTROPHIC SCLEROSIS GeneRIF:15069187 GeneRIF:15048885 GeneRIF:12039658 GeneRIF:12127151 A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts (MeSH). GeneRIF:12235108 GeneRIF:15330338 GeneRIF:15672551 GeneRIF:15657798 GeneRIF:15753080 GeneRIF:15978558 GeneRIF:15033789 amyotrophic lateral sclerosis ALS (Amyotrophic Lateral Sclerosis) Gehrigs Disease GeneRIF:15264227 GeneRIF:14596848 GeneRIF:15634772 GeneRIF:12480087 GeneRIF:12125045 A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) GeneRIF:12475980 James Malone Lou Gehrig Disease GeneRIF:15509539 GeneRIF:12230304 GeneRIF:15184633 GeneRIF:16020530 GeneRIF:11951178 DOID:332 GeneRIF:14991384 GeneRIF:12502789 GeneRIF:12659845 GeneRIF:15126567 GeneRIF:12441104 GeneRIF:15568021 Lou Gehrig's disease ICD9:335.20 GeneRIF:15789135 GeneRIF:12442272 GeneRIF:11996514 ALS GeneRIF:12770687 GeneRIF:15326253 Gehrig Disease GeneRIF:13129803 GeneRIF:15076751 GeneRIF:14978393 GeneRIF:15106121 LOU GEHRIG DIS GeneRIF:12843244 GeneRIF:15465081 NCIt:C34373 GeneRIF:15829169 LOU GEHRIGS DIS GeneRIF:15557516 GeneRIF:14734542 GeneRIF:14676054 GeneRIF:14985749 URI: http://www.ebi.ac.uk/cellline#amyotrophic_lateral_sclerosis GeneRIF:15691826 GeneRIF:15776280 GeneRIF:12915461 GeneRIF:12730211 GeneRIF:12694394 Guam Form of Amyotrophic Lateral Sclerosis Motor neuron disease, bulbar GEHRIGS DIS GeneRIF:15475574 GeneRIF:12446576 GeneRIF:15233913 GeneRIF:12707786 GeneRIF:15109247 GeneRIF:15037546 GeneRIF:11943600 MSH:D000690